What would you do to bring out the best version of yourself? In The Substance, one former Hollywood A-lister goes to extremes to recapture her youth and relive her prime.

Check out the trailer for the film below:

Here’s the official synopsis for the film:

Demi Moore gives a career best performance as Elisabeth Sparkle, a former A-lister past her prime and suddenly fired from her fitness TV show by repellent studio head Harvey (Dennis Quaid). 

She is then drawn to the opportunity presented by a mysterious new drug: THE SUBSTANCE. All it takes is one injection and she is reborn – temporarily – as the gorgeous, twentysomething Sue (Margaret Qualley). 

The only rule? Time needs to be split: exactly one week in one body, then one week in the other. No exceptions. A perfect balance. What could go wrong?

Deliriously entertaining and ruthlessly satirical, Coralie Fargeat’s Cannes sensation turns toxic beauty culture inside out with a be-careful-what-you-wish-for fable for the ages. Explosive, provocative and twisted, THE SUBSTANCE marks the arrival of a thrillingly visionary filmmaker.

The Substance premiered at Cannes Film Festival, where it took home the award for Best Screenplay. It’s also an official selection of the Toronto Film Festival. The feature comes from writer/director Coralie Fargeat.

You can catch The Substance in theaters starting September 20. Until then, check back to THS for more updates.

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